Show simple item record

Please use this identifier to cite or link to this item: http://uyr.uy.edu.mm/handle/123456789/110
dc.contributor.authorNi Ni Than
dc.contributor.authorFiebig, Heinz-Herbert
dc.contributor.authorLaatsch, Hartmut
dc.date.accessioned2016-11-07T18:10:01Z
dc.date.available2016-11-07T18:10:01Z
dc.date.issued2016
dc.identifier.urihttp://uyr.uy.edu.mm/handle/123456789/110
dc.description.abstractThe ethanol extract of the flower of Butea monosperma (Fabaceae) was found to contain butein (1), butin (2), monospermoside (3), medicarpin-3-O-glucoside (4), ß-sitosterol glucoside (5), sulphurein (6), isomonospermoside (7), isocoreopsin (8), butrin (9), isobutrin (10) ergost-5-en-3ß-ol (11), stigmasterol (12), ß-sitosterol (13), 6,10,14-trimethyl-2-pentadecanone (14), methyl hexadecanoate(15), methyl octadecanoate (16), and heptacosane (17), whose structures were determined by modern spectroscopic techniques. In which, medicarpin-3-O-glucoside (4) was isolated for the first time from this plant. The antitumour activity of three pure compounds (1), (9) and (10) were tested by using 6 human tumour cell lines. Compound (1) which showed activity in the primary screening was further screened by 36 human tumour cell lines. Compound (1) showed mean IC70 value at 11.34 µg/mL and mean IC50 value at 7.39 µg/mL in the ovarian tumour cell line.
dc.subjectButea monosperma
dc.subjectantitumour principle
dc.subjectbutein
dc.subjectmedicarpin-3-O- glucoside
dc.titleInvestigation of Bioactive Constituents and the Antitumour principle from Butea monospermalanguage
dc.typearticle


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record