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dc.contributor.authorNwet Nwet Win
dc.contributor.authorIto, Takuya
dc.contributor.authorAimaiti, Simayijiang
dc.contributor.authorKodama, Takeshi
dc.contributor.authorImagawa, Hiroshi
dc.contributor.authorHla Ngwe
dc.contributor.authorAsakawa, Yoshinori
dc.contributor.authorAbe, Ikuro
dc.contributor.authorMorita, Hiroyuki
dc.descriptionTetrahedron 71 (2015) 4707e4713
dc.description.abstractThe isolation of the CHCl3 soluble extract of Kaempferia pulchra rhizomes afforded seven new isopimarane diterpenoids, kaempulchraols IeO, together with one known analog. The structures of these compounds were elucidated using 1D and 2D NMR and X-ray diffraction analyses. The antiproliferative activity of the isolated compounds was evaluated against a panel of five human cancer cell lines. Kaempulchraol L exhibited weak antiproliferative activity against PANC-1 and PSN-1 cells with IC50 values of 39.9 and 22.6 mM, respectively.
dc.subjectKaempferia pulchra
dc.subjectIsopimarane diterpenoids
dc.subjectAntiproliferative activity
dc.titleKaempulchraols IeO: new isopimarane diterpenoids from Kaempferia pulchra rhizomes collected in Myanmar and their antiproliferative activitylanguage

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