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Please use this identifier to cite or link to this item: https://uyr.uy.edu.mm/handle/123456789/525
dc.contributor.authorAye Myint
dc.contributor.authorMyint Myint Sein
dc.contributor.authorMya Aye
dc.date.accessioned2018-03-28T11:06:21Z
dc.date.available2018-03-28T11:06:21Z
dc.date.issued2008
dc.identifier.urihttps://uyr.uy.edu.mm/handle/123456789/525
dc.descriptionI would like to express my deepest gratitude to my supervisors, Dr. Mya Aye, Rector, University of Mandalay and Dr. Myint Myint Sein, Professor and Head, Department of Chemistry, University of Mandalay, for their supervision, helpful advice, numerous invaluable suggestions and kind guidance throughout the course of this research work. I am also indebted and grateful-to Dr. Maung Htoo, Rector, University of Monywa and U Sein Win, Retire Professor, Department of Chemistry, University of Monywa for their interest in our research work as well as their kind support of the materials and constant encouragements.en
dc.description.abstractIn this Ph.D research work, one well-known Myanmar Indigenous Medicinal Plant, namely Clerodendrum serratum Spreng. (Yin-bye-net) was chosen (or preliminary phytochemical screening and antibacterial activities. In accordance with phyto test the crude extract of root of this plant responds some chemical constituents, such as, alkaloid, phenolic, lipophilic, polyphenol and glycoside, respectively. Moreover, antibacterial activities of this crude extract in various solvent systems were done by agar well diffusion method on three selected organisms (Bacillus Subtilis, Staphlococcus aureus and Pseudomonous aeruginosa). Among them ethyl acetate extract of this plant gave rise to medium activities on all tested organisms. Furthermore a pure white amorphous unknown alkaloid compound (DAM-1) was isolated from ethyl acetate extract of root of Yin-bya-net by some modem separation methods, such as Thin Layer and Column Chromatographic methods. The yield percent of this unknown alkaloid could be calculated as (0.85%) based upon the ethyl acetate crude extract. The molecular formula of this unknown potent alkaloid could be assigned as (C13H21O4N3) by some sophisticated spectroscopic methods, such as, FT-IR ,1H NMR(600 MHz), 13C NMR (I50MHz) , DEPT, HSQC and EI-Mass spectrums.en
dc.language.isoenen
dc.publisherUniversities Research Journal (URJ)en
dc.relation.ispartofseries;Vol. 1, No. 3
dc.titleIsolation and Structural Elucidation of an Unknown Biologically Active Compound from Myanmar Traditional Indigenous Medicinal Plant Clerodendrum serratum SPRENG (Yin-bya-neten
dc.typeArticleen


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